{"product_id":"crystallization-of-organic-compounds-9781119879466","title":"Crystallization of Organic Compounds","description":"\u003cb\u003eCrystallization of Organic Compounds\u003c\/b\u003e \u003cp\u003e\u003cb\u003ePractical resource covering applications of crystallization principles with methodologies, case studies, and numerous industrial examples for emphasis\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eBased on the authors' hands-on experiences as process engineers, through the use of case studies and examples of crystallization processes, ranging from laboratory development through manufacturing scale-up, \u003ci\u003eCrystallization of Organic Compounds\u003c\/i\u003e guides readers through the practical applications of crystallization and emphasizes strategies that have proven to be successful, enabling readers to avoid common pitfalls that can render standard procedures unsuccessful. \u003c\/p\u003e\u003cp\u003eMost chapters feature multiple examples that guide readers, step by step, through the crystallization of active pharmaceutical ingredients (APIs), including an analysis of the major methods of carrying out crystallization operations, their strengths and potential issues, as well as numerous examples of crystallization processes from development through manufacturing scale. \u003c\/p\u003e\u003cp\u003eAdvancements in the field of crystallization have been integrated throughout the book in the newly revised Second Edition to ensure the content adequately reflects current state-of-the-art industrial know-hows and practice. The new edition also adds chapters addressing downstream operations after the crystallization, including filtration\/washing and drying, together with industrial use cases. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eCrystallization of Organic Compounds\u003c\/i\u003e includes detailed information on: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eSolubility and solid behavior, covering phase rule, polymorph, salt\/co-crystal, chiral resolution and in-silico solubility prediction; and kinetics, covering seed, supersaturation, nucleation, crystal growth and model-based experimental design\u003c\/li\u003e \u003cli\u003eCritical issues in the crystallization practice, covering oiling out, seeding\/wet-milling, agglomeration\/aggregation, mixing scale-up and quality-by-design principles\u003c\/li\u003e \u003cli\u003eCooling, anti-solvent, evaporation and reactive crystallization process design, covering batch and continuous operations with industrial examples\u003c\/li\u003e \u003cli\u003eSpecial applications, covering crystallization with ultrasound, reaction selectivity enhancement, and computation fluid dynamics, and solid dispersion\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003eWith highly practical coverage of the subject, \u003ci\u003eCrystallization of Organic Compounds\u003c\/i\u003e is an essential resource for engineers and chemists involved with the development, scaling, or operation of crystallization process in the pharmaceutical and fine chemical industries, particularly those with degrees in chemical engineering and chemistry.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Hsien-Hsin Tung\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Wiley-Aiche\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 07\/07\/2023\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 384\u003cbr\u003e\u003cb\u003eBinding Type:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.94lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.88d\u003cbr\u003e\u003cb\u003eISBN:\u003c\/b\u003e 9781119879466\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAbout the Author\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHsien-Hsin Tung\u003c\/b\u003e, PhD, is the co-founder of AcrysPharm, LLC. He founded the crystallization lab. at Merck and center of excellence of particle engineering at Abbive. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eEdward L. Paul\u003c\/b\u003e, PhD, (deceased) was retired Director of Chemical Engineering R \u0026amp; D at Merck Research Laboratories. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eMichael Midler\u003c\/b\u003e, PhD, (deceased) was retired Senior Investigator, Chemical Engineering R\u0026amp;D at Merck. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eJames A. McCauley\u003c\/b\u003e, PhD, was a senior investigator in the Analytical R \u0026amp; D at Merck until his retirement, after which he became an adjunct professor in the Department of Chemical and Biochemical Engineering at Rutgers University.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003ci\u003eThis title is not returnable\u003c\/i\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Wiley-Aiche","offers":[{"title":"Hardcover","offer_id":41207598383219,"sku":"9.78112E+12","price":233.96,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0555\/9255\/0515\/products\/img_990daf85-8578-4720-a8b2-36451a07556d.jpg?v=1704810113","url":"https:\/\/bookstorenmore.com\/products\/crystallization-of-organic-compounds-9781119879466","provider":"Bookstore N More","version":"1.0","type":"link"}