{"product_id":"cytokines-stress-and-depression-9780306461354","title":"Cytokines, Stress, and Depression","description":"Cytokines had been characterized in the early eighties as communication mole- cules between immune cells, and between immunocytes and other peripheral cells, such as fibroblasts and endothelial cells. They play a key role in the regulation of the immune response and the coordination of the host response to infection. Based on these biological properties, nobody would have predicted that one decade later cytokines would burst upon neurosciences and permeate into several avenues of current research. In neurology, the connection between cytokines and inflammation, and the demonstration of a pivotal role of some of these molecules in cell death by apoptosis, prompted the investigation of their involvement in several neurological diseases involving an inflammatory component, including multiple sclerosis, brain trauma, stroke, and Alzheimer's disease. This movement started in the late eighties, and the corresponding field of research, known as neuroimmunology, is presently booming. In psychiatry, however, the relationship between cytokines and mental disorders was much less evident and took longer to materialize. The first indication that cytokines might be involved in psychopathology came from cancerology and internal medicine.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Robert Dantzer\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Springer\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 07\/31\/1999\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 338\u003cbr\u003e\u003cb\u003eBinding Type:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.50lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.24h x 6.62w x 0.86d\u003cbr\u003e\u003cb\u003eISBN:\u003c\/b\u003e 9780306461354\u003cp\u003e\u003ci\u003eThis title is not returnable\u003c\/i\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Springer","offers":[{"title":"Hardcover","offer_id":39952745300083,"sku":"9.78E+12","price":323.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0555\/9255\/0515\/products\/img_95e4805d-c2a5-450b-8d6e-22a49bbdec23.jpg?v=1648564814","url":"https:\/\/bookstorenmore.com\/products\/cytokines-stress-and-depression-9780306461354","provider":"Bookstore N More","version":"1.0","type":"link"}