{"product_id":"gadd45-stress-sensor-genes-9783030948061","title":"Gadd45 Stress Sensor Genes","description":"\u003cp\u003eThis second edition is fully updated throughout and covers the emerging evidence that indicates that the Gadd45 family of proteins plays a unique and critical role as sensors of stress, including genotoxic, physiological, and oncogenic stress. It sheds light on the complex cellular stress response, encompassing myriad molecular pathways with a plethora of regulators and effectors.\u003c\/p\u003e\u003cp\u003eThe GADD45 stress response genes encode small (18 kd) nuclear\/cytoplasmic proteins. These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. Despite marked similarities, Gadd45 genes are regulated differentially and exhibit functional diversity. Gadd45 proteins respond to physiological and oncogenic stress, and are implicated in cell cycle arrest, DNA demethylation and repair, apoptosis, cell survival, genomic stability, and inflammation.\u003c\/p\u003e\u003cp\u003e The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45 proteins play as stress sensors and the molecular pathways involved.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e M. Raza Zaidi\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Springer\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 05\/05\/2023\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 153\u003cbr\u003e\u003cb\u003eBinding Type:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.65lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.35d\u003cbr\u003e\u003cb\u003eISBN:\u003c\/b\u003e 9783030948061","brand":"Springer","offers":[{"title":"Paperback","offer_id":40880447324275,"sku":"9.78303E+12","price":288.66,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0555\/9255\/0515\/products\/img_5f0d918f-06d4-43f1-81d4-f14bf89b5ba7.jpg?v=1689168500","url":"https:\/\/bookstorenmore.com\/products\/gadd45-stress-sensor-genes-9783030948061","provider":"Bookstore N More","version":"1.0","type":"link"}