{"product_id":"protein-misfolding-in-neurodegenerative-diseases-mechanisms-and-therapeutic-strategies-9780367388126","title":"Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies","description":"\u003cp\u003eResearch focused on protein folding, misfolding, and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era, where a number of orphan genes have been identified for which no clear function has yet been established. This research is starting to shed light on the molecular and biochemical basis of a number of neurodegenerative diseases of dramatic impact.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProtein Misfolding in\u003c\/b\u003e \u003cb\u003eNeurodegenerative Diseases: Mechanisms and Therapeutic Strategies\u003c\/b\u003e addresses key issues concerning protein misfolding and aggregation in neurodegenerative diseases. Building on recent developments, including the recognition of protein misfolding as both a marker and a causal agent, the text presents the work of those who are actively pursuing more effective treatments, as well as preventative measures, and a possible cure. These include the use of molecular chaperones to control misfolding and novel pharmaceuticals, as well as the potential role of various inhibitors and NSAIDS. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eA Comprehensive Multifaceted Examination of the Complex Causal Agents Implicated in Protein Misfolding\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eDivided into five sections, this groundbreaking text provides up-to-date accounts for Alzheimer's, Parkinson's, Huntington's, Amyotrophic Lateral Sclerosis and Transmissible Spongiform Encephalitis. It also explores the highly likelihood that multiple factors, including oxidative stress, play a role in these complex diseases.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Robert D. E. Sewell\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/18\/2019\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 596\u003cbr\u003e\u003cb\u003eBinding Type:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.15lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.30h x 6.10w x 1.00d\u003cbr\u003e\u003cb\u003eISBN:\u003c\/b\u003e 9780367388126\u003cbr\u003e\u003cp\u003e\u003cb\u003eAbout the Author\u003c\/b\u003e\u003cbr\u003eH. John Smith, Claire Simons, Robert D. E. Sewell\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003ci\u003eThis title is not returnable\u003c\/i\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"CRC Press","offers":[{"title":"Paperback","offer_id":44214141845619,"sku":"9.78037E+12","price":144.32,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0555\/9255\/0515\/files\/img_ec3a85cd-3b01-44bf-a925-9bd88d9df30e.jpg?v=1767707310","url":"https:\/\/bookstorenmore.com\/products\/protein-misfolding-in-neurodegenerative-diseases-mechanisms-and-therapeutic-strategies-9780367388126","provider":"Bookstore N More","version":"1.0","type":"link"}