Making Mice: Standardizing Animals for American Biomedical Research, 1900-1955

Making Mice blends scientific biography, institutional history, and cultural history to show how genetically standardized mice came to play a central role in contemporary American biomedical research.

Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice.

This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. It will appeal not only to historians of science but also to biologists and medical researchers.

Author: Karen Rader
Publisher: Princeton University Press
Published: 03/21/2004
Pages: 312
Binding Type: Hardcover
Weight: 1.32lbs
Size: 9.38h x 6.16w x 0.95d
ISBN: 9780691016368

Review Citation(s):
Choice 10/01/2004 pg. 320

About the Author
Karen Rader is Marilyn Simpson Chair of Science and Society at Sarah Lawrence College.