The Biology of Oligodendrocytes

Traditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. Particular attention is paid to multiple sclerosis (MS), arguably the prime example of an acquired demyelinating disease, with detailed examinations of the current concepts regarding demyelination, oligodendroglial damage, and remyelination in MS lesions.

Author: Patricia Armati
Publisher: Cambridge University Press
Published: 10/21/2010
Pages: 304
Binding Type: Hardcover
Weight: 1.35lbs
Size: 9.10h x 6.10w x 0.90d
ISBN: 9780521899659

Review Citation(s):
Reference and Research Bk News 04/01/2011 pg. 306

About the Author
Armati, Patricia: - Patricia Armati is Associate Professor of Neuroscience and co-director of the Nerve Research Foundation, Brain and Mind Research Institute at the University of Sydney, Australia. She has a long standing interest in the cells of the nervous system and the relationship to disease and is editor of The Biology of Schwann Cells (Cambridge University Press, 2007).